RESEARCH DISPATCHES • FACULTY SYNOPSES

Gender Differences in Our Brains

Peer-reviewed syntheses examining structural tractography, hormonal receptor dynamics, and functional connectomics.

All Articles Connectivity & Synapses Hormonal Influences Cognitive Profiles Neuroplasticity & Aging

Repositorio de dispatches, notas de campo y revisiones por pares sobre neurobiología del género y conectómica cerebral.

Lead Empirical Paper

March 12, 2025 • 8 min read • DOI: 10.1016/j.neubiorev.2025.03.014

The Brain as a Mosaic: Dismantling the Binary View of Neural Architecture

Rather than segregation into dimorphic archetypes, individual human brains exhibit heterogeneous mosaics of masculine-leaning, feminine-leaning, and intermediate connectivity modules.

Male-leaning: 29% Mosaic: 40% Female-leaning: 31%

By Sarah Jenkins & Alex Chen Read Full Entry →

Peer-Reviewed Articles & Dispatches

February 14, 2025 • 6 min read • Endocrine Dynamics

Steroid Receptors & Cortical Density: Beyond Prenatal Organizing

Investigating how circulating estradiol and testosterone dynamically regulate synaptic turnover in adult human DLPFC.

By Alex Chen Read Entry →

January 29, 2025 • 11 min read • Meta-Critique & Ethics

Benjamini-Hochberg False Discovery Rates in Gender fMRI

How uncorrected p-values and small sample sizes generated two decades of spurious sex differences.

By Sarah Jenkins, Ph.D. Read Entry →

menu_book Academic Overview

The DualBrain portal synthesizes empirical connectomics, high-resolution diffusion tensor imaging, and voxel-based morphometry with strict statistical FDR correction.

IRB Protocol #24-819 • CC BY 4.0

Key Definitions

Sexual Dimorphism

Morphological differences between sexes; in humans, non-binary and largely restricted to allometric head volume scaling.

Lifespan Neuroplasticity

Neural capacity to modify axonal connectivity across development in response to experience.

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